The antiviral was found to be safe and effective following a stringent review of the available evidence.
The antiviral Lagevrio (molnupiravir) is safe and effective at reducing the risk of hospitalisation and death in people with mild to moderate COVID-19 who are at increased risk of developing severe disease, the Medicines and Healthcare products Regulatory Agency (MHRA) announced today.
This follows a rigorous review of its safety, quality and effectiveness by the UK regulator and the government’s independent expert scientific advisory body, the Commission on Human Medicines, making it the first oral antiviral for the treatment of COVID-19 to be approved.
Developed by Ridgeback Biotherapeutics and Merck Sharp & Dohme (MSD), Lagevrio works by interfering with the virus’ replication. This prevents it from multiplying, keeping virus levels low in the body and therefore reducing the severity of the disease.
Based on the clinical trial data, Lagevrio is most effective when taken during
the early stages of infection and so the MHRA recommends its use as soon as possible following a positive COVID-19 test and within five days of symptoms onsetMolnupiravir has been authorised for use in people who have mild to moderate COVID-19 and at least one risk factor for developing severe illness. Such risk factors include obesity, older age (>60 years), diabetes mellitus, or heart disease.
Health and Social Care Secretary Sajid Javid said:
“Today is a historic day for our country, as the UK is now the first country in the world to approve an antiviral that can be taken at home for COVID-19. This will be a gamechanger for the most vulnerable and the immunosuppressed, who will soon be able to receive the ground-breaking treatment.
“The UK is leading the way to research, develop and roll out the most exciting, cutting-edge treatments, and my thanks goes to the expert teams at the MHRA and MSD for this triumph, as well as the Antivirals Taskforce who have procured the treatment.
“We are working at pace across the government and with the NHS to set out plans to deploy molnupiravir to patients through a national study as soon as possible
“This antiviral will be an excellent addition to our armoury against COVID-19, and it remains vital everyone comes forward for their life-saving COVID-19 vaccine - particularly those eligible for a booster - to ensure as many people as possible are protected over the coming months.”
Dr June Raine, MHRA Chief Executive, said:
“Following a rigorous review of the data by our expert scientists and clinicians, we are satisfied that Lagevrio (molnupiravir) is safe and effective for those at risk of developing severe COVID-19 disease and have granted its approval.
“Lagevrio is another therapeutic to add to our armoury against COVID-19. It is also the world’s first approved antiviral for this disease that can be taken by mouth rather than administered intravenously. This is important, because it means it can be administered outside of a hospital setting, before COVID-19 has progressed to a severe stage.
“With no compromises on quality, safety and effectiveness, the public can trust that the MHRA has conducted a robust and thorough assessment of the data.”
Professor Sir Munir Pirmohamed, Chair of the Commission on Human Medicines, said:
“The Commission on Human Medicines and its COVID-19 Therapeutics Expert Working Group has independently reviewed the data and endorses the MHRA’s regulatory approval of Lagevrio.
“In clinical trials, Lagevrio was found to be effective in reducing the risk of hospitalisation or death for at-risk non-hospitalised adults with mild to moderate COVID-19 by 50%.
“Based on this and other data that has been carefully reviewed by the Commission and its expert group, it is clear Lagevrio is another safe and effective treatment to help us in our fight against COVID-19.”
Lagevrio is not intended to be used as a substitute for vaccination against COVID-19.
The government and the NHS will confirm how this COVID-19 treatment will be deployed to patients in due course.
ReplyDeletebayas de goji ... sí ... también las probé. para mis condiciones de salud, esas bayas rojas dulces parecían ayudar, pero solo durante el tiempo en que las consumía. No quiero tomar una droga por el resto de mi vida, entonces, ¿por qué querría tomar un suplemento natural todos los días por el resto de mi vida (aunque las bayas de goji son muy sabrosas y muy nutritivas)? para mí esto tampoco fue una cura (y estoy buscando la cura). hasta ese momento, no había encontrado una cura. Me sentí como un joven lío revuelto. Seguí teniendo un dolor extremo, pero continué en mi camino hacia la curación. Empecé a concentrarme en mí mismo y no en los demás. cuando era un adulto joven, asumí demasiadas responsabilidades por un sentido de obligación. esto ya no era saludable para mí, así que renuncié a todos mis proyectos y grupos. esos días por venir fueron los mejores [y peores] días. Me tomé mucho tiempo libre del trabajo, pero comencé a sentirme extremadamente exhausto. muchos profesionales de la salud me "diagnosticaron" fatiga suprarrenal y vih, cáncer de próstata, por lo que mi situación era molesta, entonces sigo buscando una cura permanente en línea, fue entonces cuando conocí las manos del centro de hierbas de dr itua a quienes Dios ha bendecido con hierbas ancestrales y un regalo. para curar a personas con enfermedades como cánceres, enfermedad de Alzheimer, VPH, infertilidad masculina y femenina, melanoma, mesotelioma, diabetes, mieloma múltiple, enfermedad de parkinson, tumores neuroendocrinos, herpes, vih / sida, linfoma no Hodgkin, diarrea crónica, EPOC , hechizo de amor, hepatitis ... así que hice una compra de sus medicinas a base de hierbas y he estado vigilando mi salud durante 6 años y de hecho confirmé que sus medicinas a base de hierbas son una cura permanente y estoy muy feliz de haber venido a Conozca sus curaciones a base de hierbas.Puede ponerse en contacto con el centro de hierbas del dr itua correo electrónico: drituaherbalcenter@gmail.com www.drituaherbalcenter.com whatsapp: +2348149277967. si pasaste exactamente por lo que yo paso en términos de condiciones de salud porque, para ser honesto, hay más que aprender sobre las hierbas naturales que sobre los medicamentos.